Silicone rubber in the medical field has occupied a very important position, but if the need for greater development, technical issues remained to be resolved.
Because of its sulfur water-based silicone rubber, it is still a slight sense of products after foreign body implanted in the human body. To solve this problem, surface modification methods can be used, such as silicone rubber surface coating of hydrophilic substances, or by radiation grafting method to make silicone rubber surface, or by blending with a plasma treatment or modification.
After the silicone rubber as a carrier due to the long-term implants must be removed at the expiry placed, a user's pain and increased costs, and it is difficult to ensure that all users can schedule removed, thereby increasing the risk of failure of the contraceptive. Therefore, research may lead biodegradable subcutaneous contraceptive implants, the latter have a permeability that is in a biodegradable polymer and a steroid drug, instead of silicon rubber is used as a carrier to release progesterone, progesterone release of finished carrier In vivo degradation absorbed without removal. American Triangle Institute developed a biodegradable type subcutaneous contraceptive implants Capronor (effective contraception for one year), the contraceptive efficiency, safety, acceptability, and the like with Norplant, to maintain the structural integrity of the capsule 18 to 24 months, and then start deformation, fragmentation and progressive degradation. The Biomedical Engineering Research Institute, Chinese Academy of Medical Sciences changed on the basis of Ca-pronor capsule formulation, made a subcutaneous contraceptive implants CaproF with biodegradable, has now completed the basic research and animal experiments. In short, single-type implants, biodegradable implants is a major research and development direction.
With biomedical engineering. The development of tissue engineering, technical and performance requirements for the increasing medical materials. On silicone rubber, how to make it fully used in biological engineering and tissue engineering is the main direction of future research work. Such as: The biosensor is a striking contemporary biotechnology. Miniaturization, and the adaptability of the organism such biosensor will become an important issue associated with the artificial organ.
In short, the medical silicone rubber in the life sciences, medical devices, drugs, etc. has been extensive and important applications, but there is a huge potential to be tapped, as the study of the development of life sciences and bio-materials, it will do for the human society greater contribution.
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